Singlet oxygen generation using iodinated squaraine and squaraine-rotaxane dyes

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Singlet oxygen generation using iodinated squaraine and squaraine-rotaxane dyes.

The goal of this study was to assess the ability of squaraine-rotaxanes to generate singlet oxygen for potential application in photodynamic therapy (PDT). Specifically, we compare the aggregation and photophysical properties of an iodinated squaraine dye and an iodinated squaraine-rotaxane. Even under strongly aggregating conditions, the absorption spectra of both remain relatively sharp. An X...

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New squaraine dyes for photodynamic therapy

Photodynamic therapy (PDT) [1]consists in the activation of molecular oxygen under irradiation by light in the presence of photodrugs (photosensitizers, PS) that have been previously selectively accumulated in the target tissues. In comparison with conventional treatment methods, PDT is considered to be a clinical treatment with high safety, few side effects, reliable repeatability, and relativ...

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Thermally-activated chemiluminescent squaraine rotaxane endoperoxide with green emission.

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ژورنال

عنوان ژورنال: New J. Chem.

سال: 2007

ISSN: 1144-0546,1369-9261

DOI: 10.1039/b616224j